Publications

  1. Feng M, Nanda AK, Augstein F, Zhang A, Zhao L, Malankar N, van Es SW, Blob B, Mazumdar S, Heo J, Roszak P, Hu J, Helariutta Y, Melnyk CW. 2025. The ZAT14 family promotes cell death and regulates expansins to affect xylem formation and salt tolerance in Arabidopsis. Plant Cell. (link)
  2. Wang X, Ye L, Zhang J, Melnyk CW, Mähönen AP. 2025. Hormonal regulation of cell fate plasticity of xylem-pole-pericycle lineage in Arabidopsis roots. Molecular Plant. (link)
  3. Kareem A, van Wüllen AK, Zhang A, Walckiers G, Fasth E, Melnyk CW. 2025. Water availability positions auxin response maxima to determine plant regeneration fates. Nature Plants. 11,1367-1379. (link)
  4. Augstein F, Melnyk CW. 2025. Modern and historical uses of plant grafting to engineer development, stress tolerance, chimeras, and hybrids. Plant Journal. 121(4):e70057. (link)
  5. Kokla A*, Leso M*, Simura J, Wardig C, Hayashi M, Nishii N, Tsuchiya Y, Ljung K, Melnyk CW. 2025. A long-distance inhibitory system regulates haustoria numbers in parasitic plants. * joint first authors. PNAS. 122 (8) e2424557122. (link)
  6. Mazumdar S, Augstein F, Zhang A, Musseau C, Anjam MS, Marhavy P, Melnyk CW. 2025. Damage activates EXG1 and RLP44 to suppress vascular differentiation during regeneration in Arabidopsis. Plant Communications, 101256. (link)
  7. Serivichyaswat PT, Kareem A, Feng M, Melnyk CW. 2024. Auxin signaling in the cambium promotes tissue adhesion and vascular formation during Arabidopsis graft healing. Plant Physiology, kiae257. (link)
  8. Feng M*, Zhang A*, Nguyen V, Bisht A, Almqvist C, De Veylder L, Carlsbecker A, Melnyk CW. 2024. A conserved graft formation process in Norway spruce and Arabidopsis identifies the PAT gene family as central regulators of wound healing.* joint first authors. Nature Plants. (link)
  9. Feng M, Augstein F, Kareem A, Melnyk CW. 2024. Plant Grafting: Molecular Mechanisms and Applications. Molecular Plant. (link)
  10. Melnyk CW. 2023. Quantitative regeneration: Skoog and Miller revisited. Quantitative Plant Biology 4, e10. (link)
  11. Leso M, Kokla A, Feng M, Melnyk CW. 2023. Pectin modifications promote haustoria development in the parasitic plant Phtheirospermum japonicum. Plant Physiology, kiad343. (link)
  12. Feng Q, Cubría-Radío M, Vavrdová T, De Winter F, Schilling N, Huysmans M, Nanda AK, Melnyk CW, Nowack MK. 2023. Repressive ZINC FINGER OF ARABIDOPSIS THALIANA proteins promote programmed cell death in the Arabidopsis columella root cap. Plant Physiology. kiad130. (link)
  13. Canher B, Lanssens F, Zhang A, Bisht A, Mazumdar S, Heyman J, Wolf S, Melnyk CW, De Veylder L. 2022. The regeneration factors ERF114 and ERF115 regulate auxin-mediated lateral root development in response to mechanical cues. Molecular Plant. 15 (10), 1543-1557. (link)
  14. Kokla A, Leso M, Zhang X, Simura J, Cui S, Ljung K, Yoshida S, Melnyk CW. 2022. Nitrogen represses haustoria formation through abscisic acid in the parasitic plant Phtheirospermum japonicum. Nature Communications. 13 (2976). (link)
  15. Zhang A, Matsuoka K, Kareem A, Robert M, Roszak P, Blob B, Bisht A, De Veylder L, Voiniciuc C, Asahina M, Melnyk CW. 2022. Cell-wall damage activates DOF transcription factors to promote wound healing and tissue regeneration in Arabidopsis thaliana. Current Biology. 32 (9): 1883-1894. (link)
  16. Serivichyaswat PT, Bartusch K, Leso M, Musseau C, Iwase A, Chen Y, Sugimoto K, Quint M, Melnyk CW. 2022. High temperature perception in leaves promotes vascular regeneration and graft formation in distant tissues. Development. 149 (5): dev200079. (link)
  17. Reeves G, Tripathi A, Singh P, Jones MRW, Nanda AK, Musseau C, Craze M, Bowden S, Walker JF, Bentley AR, Melnyk CW, Hibberd JM. 2022. Monocotyledonous plants graft at the embryonic root–shoot interface. Nature. 602: 280–286. (link)
  18. Roszak P, Heo JO, Blob B, Toyokura K, Sugiyama Y, Balaguer MAL, Lau W, Hamey FK, Cirrone J, Madej E, Bouatta AM, Wang X, Guichard M, Ursache R, Tavares H, Verstaen K, Wendrich J, Melnyk CW, Oda Y, Shasha D, Ahnert S, Saeys Y, De Rybel B, Heidstra R, Scheres S, Gorssmann G, Mähönen AP, Denninger P, Gottgens B, Sozzani R, Birnbaum KD, Helariutta Y. 2021. Cell-by-cell dissection of phloem development links a maturation gradient to cell specialization. Science. 374 (6575). (link)
  19. Ramachandran R, Augstein F, Mazumdar S, Nguyen TV, Minina EA, Melnyk CW, Carlsbecker A. 2021. Abscisic acid signaling activates distinct VND transcription factors to promote xylem differentiation in Arabidopsis. Current Biology. 31(14): 3153-3161. (link)
  20. Bartusch K, Melnyk CW. 2020. Insights into plant surgery: an overview of the multiple grafting techniques for Arabidopsis thaliana. Frontiers in Plant Science. 11, 2000. (link)
  21. Bartusch K, Trenner J, Melnyk CW, Quint M. 2020. Cut and paste: temperature-enhanced cotyledon micrografting for Arabidopsis thaliana seedlings. Plant Methods 16 (12). (link)
  22. De Jong M, Tavares H, Pasam RK, Butler R, Ward S, George G, Melnyk CW, Challis R, Kover PX, Leyser O. 2019. Natural variation in Arabidopsis shoot branching plasticity in response to nitrate supply affects fitness. PLoS Genetics. 15 (9), e1008366. (link)
  23. Schulze A, Zimmer M, Mielke S, Stellmach H, Melnyk CW, Hause B, Gasperini D. 2019. Wound-induced shoot-to-root relocation of JA-Ile precursors coordinates Arabidopsis growth. Molecular Plant. 12 (10): 1383-1394. (link)
  24. Miyashima S, Roszak R, Sevilem I, Toyokura K, Blob B, Heo J, Mellor N, Help-Rinta-Rahko H, Otero S, Smet W, Boekschoten M, Hooiveld G, Hashimoto K, Smetana O, Siligato R, Wallner E, Mähönen AP, Kondo Y, W Melnyk CW, Greb T, Nakajima K, Sozzani R, Bishopp A, De Rybel B, Helariutta Y. 2019. Mobile PEAR transcription factors integrate positional cues to prime cambial growth. Nature. 565: 490–494. (link)
  25. Kokla A, Melnyk CW. 2018. Developing a thief: Haustoria formation in parasitic plants. Developmental Biology. 442 (1): 53-59. (link)

  26. Melnyk CW, Gabel A, Hardcastle TJ, Robinson S, Miyashima S, Grosse I, Meyerowitz EM. 2018. Transcriptome dynamics at Arabidopsis graft junctions reveal an intertissue recognition mechanism that activates vascular regeneration. PNAS. 115(10): E2447-E2456. (link) 

  27. Landrein B, Formosa-Jordan P, Malivert A, Schuster C, Melnyk CW, Yang W, Turnbull C, Meyerowitz EM, Locke JCW, Jönsson, H. 2018. Nitrate modulates stem cell dynamics in Arabidopsis shoot meristems through cytokinins. PNAS. 115(6):1382-1387. (link)
  28. Nanda AK, Melnyk CW. 2018. The role of plant hormones during grafting. Journal of Plant Research. 131(1):49-58. (link)
  29. Bagchi R, Melnyk CW, Christ G, Winkler M, Kirchsteiner K, Salehin M, Mergner J, Niemeyer M, Schwechheimer C, Calderón Villalobos LIA, Estelle M. 2017. The Arabidopsis ALF4 protein is a regulator of SCF E3 ligases. The EMBO Journal. 37(2):255-268. (link)
  30. Spallek T*, Melnyk CW*, Wakatake T, Zhang J, Sakamoto Y, Kiba T, Yoshida S, Matsunaga S, Sakakibara H, Shirasu K. 2017. Interspecies hormonal control of host root morphology by parasitic plants. PNAS. 114(20):5283-5288. * joint first author. (link)
  31. Melnyk CW. 2017. Monitoring vascular regeneration and xylem connectivity in Arabidopsis thaliana. Xylem, part of Methods in Molecular Biology. Volume 1544, pg 91-102. Publisher: Springer. (link)
  32. Melnyk CW. 2017. Grafting with Arabidopsis thaliana. Plant Hormones: Third Edition, part of Methods in Molecular Biology. Volume 1497, pg 9-18. Publisher: Springer. (link)
  33. Melnyk CW. 2017. Plant grafting: Insights into tissue regeneration. Regeneration. 4(1):3-14. (link)
  34. Melnyk CW. 2017. Connecting the plant vasculature to friend or foe. New Phytologist. 213(4):1611-1617. (link)
  35. Lewsey M, Hardcastle T, Melnyk CW, Molnar A, Valli A, Urich M, Nery J, Baulcombe D, Ecker J. 2016. Mobile small RNAs regulate genome-wide DNA methylation. PNAS. 113 (6): E801-810. (link)
  36. Randall RS, Miyashima S, Blomster T, Zhang J, Karlberg A, Immanen J, Immanen K, Lee J, Kakimoto T, Blajecka K, Melnyk CW, Alcasabas A, Forzani C, Matsumoto-Kitano M, Mahonen AP, Bahlerao R, Dewitte W, Helariutta Y, Murray JAH. 2015. AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins. Biology Open. 4(10):1229-36. (link)
  37. Melnyk CW, Schuster C, Leyser O, Meyerowitz EM. 2015. A developmental framework for graft formation and vascular reconnection in Arabidopsis thaliana. Current Biology. 25(10):1306-1318. (link)
  38. Müller D, Waldie T, Miyawaki K, To JPC, Melnyk CW, Kieber JJ, Kakimoto T, Leyser O. 2015. Cytokinin is required for escape but not release from auxin mediated apical dominance. The Plant Journal. 82(5): 874-886. (link)
  39. Melnyk CW, Meyerowitz EM. 2015. Plant grafting. Current Biology. 25(5):183-188. (link)
  40. Melnyk CW, Harris CJ. 2013. RNA Silencing in Plants. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Publisher, John Wiley & Sons. (link)
  41. Dunoyer P, Melnyk C, Molnar A, Slotkin, RK. 2013. Plant Mobile Small RNAs. Cold Spring Harbor Perspectives in Biology. 1;5(7). (link)
  42. Melnyk CW*, Molnar A*, Bassett A, Baulcombe DC. 2011. Mobile 24 nt small RNAs direct transcriptional gene silencing in the root meristems of Arabidopsis thaliana. Current Biology. 21(19):1678-83. * – joint first author (link)
  43. Melnyk CW, Molnar A, Baulcombe DC. 2011. Intercellular and systemic movement of RNA silencing signals. EMBO J. 30(17):3553-63. (link)
  44. Molnar A, Melnyk C, Baulcombe DC. 2011. Silencing signals in plants: a long journey for small RNAs. Genome Biology. 12(1):215. (link)
  45. Molnar A*, Melnyk CW*, Bassett A, Hardcastle T, Dunn R, Baulcombe DC. 2010. Small silencing RNAs in plants are mobile and direct epigenetic modification in recipient cells. Science 328(5980):872-5. * – joint first author (link)
  46. Searle I, Pontes O, Melnyk CW, Smith L, Baulcombe, DC. 2010. JMJ14, a JmjC domain protein, is required for RNA silencing and cell-to-cell movement of an RNA silencing signal in Arabidopsis. Genes and Development. 24(10):986-91. (link)
  47. Mosher RA, Melnyk CW. 2010. siRNAs and DNA Methylation: Seedy Epigenetics. Trends in Plant Science (4):204-10. (link)
  48. Mosher RA, Melnyk CW, Kelly KA, Dunn RM, Studholme DJ, Baulcombe DC. 2009. Uniparental expression of PolIV-dependent siRNAs in developing endosperm of Arabidopsis. Nature 460(7252):283-6. (link)
  49. Loit E, Melnyk CW, Macfarlane AJ, Scott FW, Altosaar I. 2009. Identification of three wheat globulin genes by screening a Triticum aestivum BAC genomic library with cDNA from a diabetes-associated globulin. BMC Plant Biology 9(1):93. (link)
  50. Feiz, L, Wanjugi HW, Melnyk CW, Altosaar I, Martin JM, Giroux MJ. 2009. Puroindolines co-localize to the starch granule surface and increase seed bound polar lipid content. Journal of Cereal Science 50:91-98. (link)
  51. Searle IR, Mosher RA, Melnyk CW, Baulcombe DC. 2007. Small RNAs hit the big time. New Phytologist 174:479-482. (link)